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TMTC2-GNA14 Fusion FISH Probe

The TMTC2-GNA14 Fusion FISH Probe is used to confirm a fusion of the TMTC2 and GNA14 genes. The fusion of the TMTC2 and GNA14 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TMTC2-GNA14-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TMTC2-GNA14-20-RERE 20 (40 μL) 200 μL
TMTC2-GNA14-20-REOR 20 (40 μL) 200 μL
TMTC2-GNA14-20-REGO 20 (40 μL) 200 μL
TMTC2-GNA14-20-REGR 20 (40 μL) 200 μL
TMTC2-GNA14-20-REAQ 20 (40 μL) 200 μL
TMTC2-GNA14-20-ORRE 20 (40 μL) 200 μL
TMTC2-GNA14-20-OROR 20 (40 μL) 200 μL
TMTC2-GNA14-20-ORGO 20 (40 μL) 200 μL
TMTC2-GNA14-20-ORAQ 20 (40 μL) 200 μL
TMTC2-GNA14-20-GORE 20 (40 μL) 200 μL
TMTC2-GNA14-20-GOOR 20 (40 μL) 200 μL
TMTC2-GNA14-20-GOGO 20 (40 μL) 200 μL
TMTC2-GNA14-20-GOGR 20 (40 μL) 200 μL
TMTC2-GNA14-20-GOAQ 20 (40 μL) 200 μL
TMTC2-GNA14-20-GRRE 20 (40 μL) 200 μL
TMTC2-GNA14-20-GROR 20 (40 μL) 200 μL
TMTC2-GNA14-20-GRGO 20 (40 μL) 200 μL
TMTC2-GNA14-20-GRGR 20 (40 μL) 200 μL
TMTC2-GNA14-20-GRAQ 20 (40 μL) 200 μL
TMTC2-GNA14-20-AQRE 20 (40 μL) 200 μL
TMTC2-GNA14-20-AQOR 20 (40 μL) 200 μL
TMTC2-GNA14-20-AQGO 20 (40 μL) 200 μL
TMTC2-GNA14-20-AQGR 20 (40 μL) 200 μL
TMTC2-GNA14-20-AQAQ 20 (40 μL) 200 μL

GNA14 Gene Summary

This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors.[provided by RefSeq, Feb 2009]

Gene Name: G Protein Subunit Alpha 14

Chromosome: CHR9: 80037994 -80263232

Locus: 9q21.2

TMTC2 Gene Summary

The protein encoded by this gene is an integral membrane protein localized to the endoplasmic reticulum (ER). The encoded protein contains many tetratricopeptide repeats, sequences known for being involved in protein-protein interactions. This protein binds both the calcium uptake pump SERCA2B and the carbohydrate-binding chaperone calnexin, and it appears to play a role in calcium homeostasis in the ER. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

Gene Name: Transmembrane And Tetratricopeptide Repeat Containing 2

Chromosome: CHR12: 83080933 -83528067

Locus: 12q21.31

Gene Diseases

The TMTC2 GNA14 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.