TNC-CDH3 Fusion FISH Probe
The TNC-CDH3 Fusion FISH Probe is used to confirm a fusion of the TNC and CDH3 genes. The fusion of the TNC and CDH3 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TNC-CDH3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-RERE | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-REOR | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-REGO | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-REGR | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-REAQ | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-ORRE | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-OROR | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-ORGO | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-ORAQ | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-GORE | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-GOOR | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-GOGO | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-GOGR | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-GOAQ | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-GRRE | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-GROR | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-GRGO | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-GRGR | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-GRAQ | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-AQRE | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-AQOR | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-AQGO | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-AQGR | 20 (40 μL) | 200 μL |
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| TNC-CDH3-20-AQAQ | 20 (40 μL) | 200 μL |
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CDH3 Gene Summary
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015]
Gene Name: Cadherin 3
Chromosome: CHR16: 68678150 -68732957
Locus: 16q22.1
TNC Gene Summary
This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity, and neuronal regeneration. [provided by RefSeq, Jul 2011]
Gene Name: Tenascin C
Chromosome: CHR9: 117781853 -117880536
Locus: 9q33.1
Gene Diseases
The TNC CDH3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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