TNIP1-ANXA6 Fusion FISH Probe
The TNIP1-ANXA6 Fusion FISH Probe is used to confirm a fusion of the TNIP1 and ANXA6 genes. The fusion of the TNIP1 and ANXA6 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TNIP1-ANXA6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-RERE | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-REOR | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-REGO | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-REGR | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-REAQ | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-ORRE | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-OROR | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-ORGO | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-ORAQ | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-GORE | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-GOOR | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-GOGO | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-GOGR | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-GOAQ | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-GRRE | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-GROR | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-GRGO | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-GRGR | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-GRAQ | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-AQRE | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-AQOR | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-AQGO | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-AQGR | 20 (40 μL) | 200 μL |
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| TNIP1-ANXA6-20-AQAQ | 20 (40 μL) | 200 μL |
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ANXA6 Gene Summary
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010]
Gene Name: Annexin A6
Chromosome: CHR5: 150480266 -150537443
Locus: 5q33.1
TNIP1 Gene Summary
This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Name: TNFAIP3 Interacting Protein 1
Chromosome: CHR5: 150409505 -150460997
Locus: 5q33.1
Gene Diseases
The TNIP1 ANXA6 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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