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TNS1-RNF25 Fusion FISH Probe

The TNS1-RNF25 Fusion FISH Probe is used to confirm a fusion of the TNS1 and RNF25 genes. The fusion of the TNS1 and RNF25 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TNS1-RNF25-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TNS1-RNF25-20-RERE 20 (40 μL) 200 μL
TNS1-RNF25-20-REOR 20 (40 μL) 200 μL
TNS1-RNF25-20-REGO 20 (40 μL) 200 μL
TNS1-RNF25-20-REGR 20 (40 μL) 200 μL
TNS1-RNF25-20-REAQ 20 (40 μL) 200 μL
TNS1-RNF25-20-ORRE 20 (40 μL) 200 μL
TNS1-RNF25-20-OROR 20 (40 μL) 200 μL
TNS1-RNF25-20-ORGO 20 (40 μL) 200 μL
TNS1-RNF25-20-ORAQ 20 (40 μL) 200 μL
TNS1-RNF25-20-GORE 20 (40 μL) 200 μL
TNS1-RNF25-20-GOOR 20 (40 μL) 200 μL
TNS1-RNF25-20-GOGO 20 (40 μL) 200 μL
TNS1-RNF25-20-GOGR 20 (40 μL) 200 μL
TNS1-RNF25-20-GOAQ 20 (40 μL) 200 μL
TNS1-RNF25-20-GRRE 20 (40 μL) 200 μL
TNS1-RNF25-20-GROR 20 (40 μL) 200 μL
TNS1-RNF25-20-GRGO 20 (40 μL) 200 μL
TNS1-RNF25-20-GRGR 20 (40 μL) 200 μL
TNS1-RNF25-20-GRAQ 20 (40 μL) 200 μL
TNS1-RNF25-20-AQRE 20 (40 μL) 200 μL
TNS1-RNF25-20-AQOR 20 (40 μL) 200 μL
TNS1-RNF25-20-AQGO 20 (40 μL) 200 μL
TNS1-RNF25-20-AQGR 20 (40 μL) 200 μL
TNS1-RNF25-20-AQAQ 20 (40 μL) 200 μL

TNS1 Gene Summary

The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

Gene Name: Tensin 1

Chromosome: CHR2: 218664511 -218808796

Locus: 2q35

RNF25 Gene Summary

The protein encoded by this gene contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination. [provided by RefSeq, Jul 2008]

Gene Name: Ring Finger Protein 25

Chromosome: CHR2: 219528586 -219536781

Locus: 2q35

Gene Diseases

The TNS1 RNF25 Fusion has been associated with the following diseases:

Disease Name
Uterine Corpus Endometrial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.