TNS1-TMBIM1 Fusion FISH Probe
The TNS1-TMBIM1 Fusion FISH Probe is used to confirm a fusion of the TNS1 and TMBIM1 genes. The fusion of the TNS1 and TMBIM1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TNS1-TMBIM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-RERE | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-REOR | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-REGO | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-REGR | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-REAQ | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-ORRE | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-OROR | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-ORGO | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-GORE | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-GOOR | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-GOGO | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-GOGR | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-GRRE | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-GROR | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-GRGO | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-GRGR | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-AQRE | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-AQOR | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-AQGO | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-AQGR | 20 (40 μL) | 200 μL |
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| TNS1-TMBIM1-20-AQAQ | 20 (40 μL) | 200 μL |
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TNS1 Gene Summary
The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Gene Name: Tensin 1
Chromosome: CHR2: 218664511 -218808796
Locus: 2q35
TMBIM1 Gene Summary
The Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1) gene is located on chr2 :219138916-219157280 at 2q35.
Gene Name: Transmembrane BAX Inhibitor Motif Containing 1
Chromosome: CHR2: 219138916 -219157280
Locus: 2q35
Gene Diseases
The TNS1 TMBIM1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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