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TOB2-ACO2 Fusion FISH Probe

The TOB2-ACO2 Fusion FISH Probe is used to confirm a fusion of the TOB2 and ACO2 genes. The fusion of the TOB2 and ACO2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TOB2-ACO2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TOB2-ACO2-20-RERE 20 (40 μL) 200 μL
TOB2-ACO2-20-REOR 20 (40 μL) 200 μL
TOB2-ACO2-20-REGO 20 (40 μL) 200 μL
TOB2-ACO2-20-REGR 20 (40 μL) 200 μL
TOB2-ACO2-20-REAQ 20 (40 μL) 200 μL
TOB2-ACO2-20-ORRE 20 (40 μL) 200 μL
TOB2-ACO2-20-OROR 20 (40 μL) 200 μL
TOB2-ACO2-20-ORGO 20 (40 μL) 200 μL
TOB2-ACO2-20-ORAQ 20 (40 μL) 200 μL
TOB2-ACO2-20-GORE 20 (40 μL) 200 μL
TOB2-ACO2-20-GOOR 20 (40 μL) 200 μL
TOB2-ACO2-20-GOGO 20 (40 μL) 200 μL
TOB2-ACO2-20-GOGR 20 (40 μL) 200 μL
TOB2-ACO2-20-GOAQ 20 (40 μL) 200 μL
TOB2-ACO2-20-GRRE 20 (40 μL) 200 μL
TOB2-ACO2-20-GROR 20 (40 μL) 200 μL
TOB2-ACO2-20-GRGO 20 (40 μL) 200 μL
TOB2-ACO2-20-GRGR 20 (40 μL) 200 μL
TOB2-ACO2-20-GRAQ 20 (40 μL) 200 μL
TOB2-ACO2-20-AQRE 20 (40 μL) 200 μL
TOB2-ACO2-20-AQOR 20 (40 μL) 200 μL
TOB2-ACO2-20-AQGO 20 (40 μL) 200 μL
TOB2-ACO2-20-AQGR 20 (40 μL) 200 μL
TOB2-ACO2-20-AQAQ 20 (40 μL) 200 μL

ACO2 Gene Summary

The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008]

Gene Name: Aconitase 2

Chromosome: CHR22: 41865128 -41924993

Locus: 22q13.2

TOB2 Gene Summary

TOB2 belongs to the TOB (see TOB1; MIM 605523)/BTG1 (MIM 109580) family of antiproliferative proteins, which are involved in the regulation of cell cycle progression.[supplied by OMIM, Apr 2004]

Gene Name: Transducer Of ERBB2, 2

Chromosome: CHR22: 41829491 -41843027

Locus: 22q13.2

Gene Diseases

The TOB2 ACO2 Fusion has been associated with the following diseases:

Disease Name
Uterine Corpus Endometrial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.