TOP1-CA10 Fusion FISH Probe
The TOP1-CA10 Fusion FISH Probe is used to confirm a fusion of the TOP1 and CA10 genes. The fusion of the TOP1 and CA10 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TOP1-CA10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-RERE | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-REOR | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-REGO | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-REGR | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-OROR | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-GORE | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-GROR | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| TOP1-CA10-20-AQAQ | 20 (40 μL) | 200 μL |
|
TOP1 Gene Summary
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008]
Gene Name: DNA Topoisomerase I
Chromosome: CHR20: 39657461 -39753126
Locus: 20q12
CA10 Gene Summary
This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Carbonic Anhydrase 10
Chromosome: CHR17: 49707673 -50237377
Locus: 17q21.33-q22
Gene Diseases
The TOP1 CA10 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|