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TP63-LEPREL1 Fusion FISH Probe

The TP63-LEPREL1 Fusion FISH Probe is used to confirm a fusion of the TP63 and LEPREL1 genes. The fusion of the TP63 and LEPREL1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TP63-LEPREL1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TP63-LEPREL1-20-RERE 20 (40 μL) 200 μL
TP63-LEPREL1-20-REOR 20 (40 μL) 200 μL
TP63-LEPREL1-20-REGO 20 (40 μL) 200 μL
TP63-LEPREL1-20-REGR 20 (40 μL) 200 μL
TP63-LEPREL1-20-REAQ 20 (40 μL) 200 μL
TP63-LEPREL1-20-ORRE 20 (40 μL) 200 μL
TP63-LEPREL1-20-OROR 20 (40 μL) 200 μL
TP63-LEPREL1-20-ORGO 20 (40 μL) 200 μL
TP63-LEPREL1-20-ORAQ 20 (40 μL) 200 μL
TP63-LEPREL1-20-GORE 20 (40 μL) 200 μL
TP63-LEPREL1-20-GOOR 20 (40 μL) 200 μL
TP63-LEPREL1-20-GOGO 20 (40 μL) 200 μL
TP63-LEPREL1-20-GOGR 20 (40 μL) 200 μL
TP63-LEPREL1-20-GOAQ 20 (40 μL) 200 μL
TP63-LEPREL1-20-GRRE 20 (40 μL) 200 μL
TP63-LEPREL1-20-GROR 20 (40 μL) 200 μL
TP63-LEPREL1-20-GRGO 20 (40 μL) 200 μL
TP63-LEPREL1-20-GRGR 20 (40 μL) 200 μL
TP63-LEPREL1-20-GRAQ 20 (40 μL) 200 μL
TP63-LEPREL1-20-AQRE 20 (40 μL) 200 μL
TP63-LEPREL1-20-AQOR 20 (40 μL) 200 μL
TP63-LEPREL1-20-AQGO 20 (40 μL) 200 μL
TP63-LEPREL1-20-AQGR 20 (40 μL) 200 μL
TP63-LEPREL1-20-AQAQ 20 (40 μL) 200 μL

TP63 Gene Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. [provided by RefSeq, Aug 2016]

Gene Name: Tumor Protein P63

Chromosome: CHR3: 189349215 -189615068

Locus: 3q28

Gene Diseases

The TP63 LEPREL1 Fusion has been associated with the following diseases:

Disease Name
Head And Neck Squamous Cell Carcinoma 

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.