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TPCN2-TMEM179B Fusion FISH Probe

The TPCN2-TMEM179B Fusion FISH Probe is used to confirm a fusion of the TPCN2 and TMEM179B genes. The fusion of the TPCN2 and TMEM179B genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TPCN2-TMEM179B-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-RERE 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-REOR 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-REGO 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-REGR 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-REAQ 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-ORRE 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-OROR 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-ORGO 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-ORAQ 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-GORE 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-GOOR 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-GOGO 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-GOGR 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-GOAQ 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-GRRE 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-GROR 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-GRGO 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-GRGR 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-GRAQ 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-AQRE 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-AQOR 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-AQGO 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-AQGR 20 (40 μL) 200 μL
TPCN2-TMEM179B-20-AQAQ 20 (40 μL) 200 μL

TPCN2 Gene Summary

This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.[provided by RefSeq, Dec 2009]

Gene Name: Two Pore Segment Channel 2

Chromosome: CHR11: 68816349 -68858072

Locus: 11q13.3

TMEM179B Gene Summary

The Transmembrane Protein 179B (TMEM179B) gene is located on chr11 :62554873-62557872 at 11q12.3.

Gene Name: Transmembrane Protein 179B

Chromosome: CHR11: 62554873 -62557872

Locus: 11q12.3

Gene Diseases

The TPCN2 TMEM179B Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.