TPX2-MECOM Fusion FISH Probe
The TPX2-MECOM Fusion FISH Probe is used to confirm a fusion of the TPX2 and MECOM genes. The fusion of the TPX2 and MECOM genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TPX2-MECOM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-RERE | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-REOR | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-REGO | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-REGR | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-REAQ | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-ORRE | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-OROR | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-ORGO | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-ORAQ | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-GORE | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-GOOR | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-GOGO | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-GOGR | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-GOAQ | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-GRRE | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-GROR | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-GRGO | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-GRGR | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-GRAQ | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-AQRE | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-AQOR | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-AQGO | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-AQGR | 20 (40 μL) | 200 μL |
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| TPX2-MECOM-20-AQAQ | 20 (40 μL) | 200 μL |
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MECOM Gene Summary
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Gene Name: MDS1 And EVI1 Complex Locus
Chromosome: CHR3: 168801286 -169381563
Locus: 3q26.2
TPX2 Gene Summary
The TPX2, Microtubule Nucleation Factor (TPX2) gene is located on chr20 :30326903-30389603 at 20q11.21.
Gene Name: TPX2, Microtubule Nucleation Factor
Chromosome: CHR20: 30326903 -30389603
Locus: 20q11.21
Gene Diseases
The TPX2 MECOM Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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