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TRERF1-GNMT Fusion FISH Probe

The TRERF1-GNMT Fusion FISH Probe is used to confirm a fusion of the TRERF1 and GNMT genes. The fusion of the TRERF1 and GNMT genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TRERF1-GNMT-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TRERF1-GNMT-20-RERE 20 (40 μL) 200 μL
TRERF1-GNMT-20-REOR 20 (40 μL) 200 μL
TRERF1-GNMT-20-REGO 20 (40 μL) 200 μL
TRERF1-GNMT-20-REGR 20 (40 μL) 200 μL
TRERF1-GNMT-20-REAQ 20 (40 μL) 200 μL
TRERF1-GNMT-20-ORRE 20 (40 μL) 200 μL
TRERF1-GNMT-20-OROR 20 (40 μL) 200 μL
TRERF1-GNMT-20-ORGO 20 (40 μL) 200 μL
TRERF1-GNMT-20-ORAQ 20 (40 μL) 200 μL
TRERF1-GNMT-20-GORE 20 (40 μL) 200 μL
TRERF1-GNMT-20-GOOR 20 (40 μL) 200 μL
TRERF1-GNMT-20-GOGO 20 (40 μL) 200 μL
TRERF1-GNMT-20-GOGR 20 (40 μL) 200 μL
TRERF1-GNMT-20-GOAQ 20 (40 μL) 200 μL
TRERF1-GNMT-20-GRRE 20 (40 μL) 200 μL
TRERF1-GNMT-20-GROR 20 (40 μL) 200 μL
TRERF1-GNMT-20-GRGO 20 (40 μL) 200 μL
TRERF1-GNMT-20-GRGR 20 (40 μL) 200 μL
TRERF1-GNMT-20-GRAQ 20 (40 μL) 200 μL
TRERF1-GNMT-20-AQRE 20 (40 μL) 200 μL
TRERF1-GNMT-20-AQOR 20 (40 μL) 200 μL
TRERF1-GNMT-20-AQGO 20 (40 μL) 200 μL
TRERF1-GNMT-20-AQGR 20 (40 μL) 200 μL
TRERF1-GNMT-20-AQAQ 20 (40 μL) 200 μL

GNMT Gene Summary

The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. This protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia). Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between the upstream CNPY3 (canopy FGF signaling regulator 3) gene and this gene and is represented with GeneID:107080644. [provided by RefSeq, Jan 2016]

Gene Name: Glycine N-methyltransferase

Chromosome: CHR6: 42928499 -42931618

Locus: 6p21.1

TRERF1 Gene Summary

This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

Gene Name: Transcriptional Regulating Factor 1

Chromosome: CHR6: 42192668 -42419783

Locus: 6p21.1

Gene Diseases

The TRERF1 GNMT Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.