TRIB1-NSMCE2 Fusion FISH Probe
The TRIB1-NSMCE2 Fusion FISH Probe is used to confirm a fusion of the TRIB1 and NSMCE2 genes. The fusion of the TRIB1 and NSMCE2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRIB1-NSMCE2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-RERE | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-REOR | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-REGO | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-REGR | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-REAQ | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-ORRE | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-OROR | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-ORGO | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-GORE | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-GOOR | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-GOGO | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-GOGR | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-GRRE | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-GROR | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-GRGO | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-GRGR | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-AQRE | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-AQOR | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-AQGO | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-AQGR | 20 (40 μL) | 200 μL |
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| TRIB1-NSMCE2-20-AQAQ | 20 (40 μL) | 200 μL |
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TRIB1 Gene Summary
The Tribbles Pseudokinase 1 (TRIB1) gene is located on chr8 :126442562-126450644 at 8q24.13.
Gene Name: Tribbles Pseudokinase 1
Chromosome: CHR8: 126442562 -126450644
Locus: 8q24.13
NSMCE2 Gene Summary
This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance. [provided by RefSeq, Mar 2017]
Gene Name: NSE2/MMS21 Homolog, SMC5-SMC6 Complex SUMO Ligase
Chromosome: CHR8: 126104082 -126379367
Locus: 8q24.13
Gene Diseases
The TRIB1 NSMCE2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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