TRIM2-WDR37 Fusion FISH Probe
The TRIM2-WDR37 Fusion FISH Probe is used to confirm a fusion of the TRIM2 and WDR37 genes. The fusion of the TRIM2 and WDR37 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRIM2-WDR37-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-RERE | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-REOR | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-REGO | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-REGR | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-REAQ | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-ORRE | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-OROR | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-ORGO | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-GORE | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-GOOR | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-GOGO | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-GOGR | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-GRRE | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-GROR | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-GRGO | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-GRGR | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-AQRE | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-AQOR | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-AQGO | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-AQGR | 20 (40 μL) | 200 μL |
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| TRIM2-WDR37-20-AQAQ | 20 (40 μL) | 200 μL |
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WDR37 Gene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]
Gene Name: WD Repeat Domain 37
Chromosome: CHR10: 1102775 -1178237
Locus: 10p15.3
TRIM2 Gene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Gene Name: Tripartite Motif Containing 2
Chromosome: CHR4: 154074269 -154260474
Locus: 4q31.3
Gene Diseases
The TRIM2 WDR37 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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