TRIM24-ULK4 Fusion FISH Probe
The TRIM24-ULK4 Fusion FISH Probe is used to confirm a fusion of the TRIM24 and ULK4 genes. The fusion of the TRIM24 and ULK4 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRIM24-ULK4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-RERE | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-REOR | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-REGO | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-REGR | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-REAQ | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-ORRE | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-OROR | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-ORGO | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-GORE | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-GOOR | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-GOGO | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-GOGR | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-GRRE | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-GROR | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-GRGO | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-GRGR | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-AQRE | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-AQOR | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-AQGO | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-AQGR | 20 (40 μL) | 200 μL |
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| TRIM24-ULK4-20-AQAQ | 20 (40 μL) | 200 μL |
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TRIM24 Gene Summary
The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Tripartite Motif Containing 24
Chromosome: CHR7: 138145078 -138270332
Locus: 7q33-q34
ULK4 Gene Summary
This gene encodes a member of the unc-51-like serine/threonine kinase (STK) family. Members of this protein family play a role in neuronal growth and endocytosis. The encoded protein is likely involved in neurite branching, neurite elongation and neuronal migration. Genome-wide association studies (GWAS) indicate an association of variations in this gene with blood pressure and hypertension. Sequence variations in this gene may also be be associated with psychiatric disorders, including schizophrenia and bipolar disorder. Pseudogenes associated with this gene have been identified and are located on chromosome 15. [provided by RefSeq, Jul 2016]
Gene Name: Unc-51 Like Kinase 4
Chromosome: CHR3: 41288089 -42003660
Locus: 3p22.1
Gene Diseases
The TRIM24 ULK4 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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