TRIO-CLNK Fusion FISH Probe
The TRIO-CLNK Fusion FISH Probe is used to confirm a fusion of the TRIO and CLNK genes. The fusion of the TRIO and CLNK genes has been associated with Skin Cutaneous Melanoma, and Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRIO-CLNK-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-RERE | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-REOR | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-REGO | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-REGR | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-REAQ | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-ORRE | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-OROR | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-ORGO | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-GORE | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-GOOR | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-GOGO | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-GOGR | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-GRRE | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-GROR | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-GRGO | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-GRGR | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-AQRE | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-AQOR | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-AQGO | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-AQGR | 20 (40 μL) | 200 μL |
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| TRIO-CLNK-20-AQAQ | 20 (40 μL) | 200 μL |
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TRIO Gene Summary
This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: Trio Rho Guanine Nucleotide Exchange Factor
Chromosome: CHR5: 14143828 -14509458
Locus: 5p15.2
CLNK Gene Summary
MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 [PubMed 10562326]; Goitsuka et al., 2000, 2001 [PubMed 10744659] [PubMed 11463797]).[supplied by OMIM, Mar 2008]
Gene Name: Cytokine Dependent Hematopoietic Cell Linker
Chromosome: CHR4: 10491837 -10686386
Locus: 4p16.1
Gene Diseases
The TRIO CLNK Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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