TXN-NDST3 Fusion FISH Probe
The TXN-NDST3 Fusion FISH Probe is used to confirm a fusion of the TXN and NDST3 genes. The fusion of the TXN and NDST3 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TXN-NDST3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-RERE | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-REOR | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-REGO | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-REGR | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-REAQ | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-ORRE | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-OROR | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-ORGO | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-ORAQ | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-GORE | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-GOOR | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-GOGO | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-GOGR | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-GOAQ | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-GRRE | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-GROR | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-GRGO | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-GRGR | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-GRAQ | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-AQRE | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-AQOR | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-AQGO | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-AQGR | 20 (40 μL) | 200 μL |
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| TXN-NDST3-20-AQAQ | 20 (40 μL) | 200 μL |
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TXN Gene Summary
The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Thioredoxin
Chromosome: CHR9: 113006309 -113018778
Locus: 9q31.3
NDST3 Gene Summary
This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. This monomeric bifunctional enzyme catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate and heparin, which are the initial chemical modifications required for the biosynthesis of the functional oligosaccharide sequences that define the specific ligand binding activities of heparan sulfate and heparin. [provided by RefSeq, Nov 2008]
Gene Name: N-deacetylase And N-sulfotransferase 3
Chromosome: CHR4: 118955499 -119179789
Locus: 4q26
Gene Diseases
The TXN NDST3 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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