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TYK2-TMEM205 Fusion FISH Probe

The TYK2-TMEM205 Fusion FISH Probe is used to confirm a fusion of the TYK2 and TMEM205 genes. The fusion of the TYK2 and TMEM205 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TYK2-TMEM205-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TYK2-TMEM205-20-RERE 20 (40 μL) 200 μL
TYK2-TMEM205-20-REOR 20 (40 μL) 200 μL
TYK2-TMEM205-20-REGO 20 (40 μL) 200 μL
TYK2-TMEM205-20-REGR 20 (40 μL) 200 μL
TYK2-TMEM205-20-REAQ 20 (40 μL) 200 μL
TYK2-TMEM205-20-ORRE 20 (40 μL) 200 μL
TYK2-TMEM205-20-OROR 20 (40 μL) 200 μL
TYK2-TMEM205-20-ORGO 20 (40 μL) 200 μL
TYK2-TMEM205-20-ORAQ 20 (40 μL) 200 μL
TYK2-TMEM205-20-GORE 20 (40 μL) 200 μL
TYK2-TMEM205-20-GOOR 20 (40 μL) 200 μL
TYK2-TMEM205-20-GOGO 20 (40 μL) 200 μL
TYK2-TMEM205-20-GOGR 20 (40 μL) 200 μL
TYK2-TMEM205-20-GOAQ 20 (40 μL) 200 μL
TYK2-TMEM205-20-GRRE 20 (40 μL) 200 μL
TYK2-TMEM205-20-GROR 20 (40 μL) 200 μL
TYK2-TMEM205-20-GRGO 20 (40 μL) 200 μL
TYK2-TMEM205-20-GRGR 20 (40 μL) 200 μL
TYK2-TMEM205-20-GRAQ 20 (40 μL) 200 μL
TYK2-TMEM205-20-AQRE 20 (40 μL) 200 μL
TYK2-TMEM205-20-AQOR 20 (40 μL) 200 μL
TYK2-TMEM205-20-AQGO 20 (40 μL) 200 μL
TYK2-TMEM205-20-AQGR 20 (40 μL) 200 μL
TYK2-TMEM205-20-AQAQ 20 (40 μL) 200 μL

TYK2 Gene Summary

This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]

Gene Name: Tyrosine Kinase 2

Chromosome: CHR19: 10461203 -10491248

Locus: 19p13.2

TMEM205 Gene Summary

The Transmembrane Protein 205 (TMEM205) gene is located on chr19 :11453451-11456981 at 19p13.2.

Gene Name: Transmembrane Protein 205

Chromosome: CHR19: 11453451 -11456981

Locus: 19p13.2

Gene Diseases

The TYK2 TMEM205 Fusion has been associated with the following diseases:

Disease Name
Esophageal Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.