UBA1-ELK3 Fusion FISH Probe
The UBA1-ELK3 Fusion FISH Probe is used to confirm a fusion of the UBA1 and ELK3 genes. The fusion of the UBA1 and ELK3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBA1-ELK3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-RERE | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-REOR | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-REGO | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-REGR | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-REAQ | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-ORRE | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-OROR | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-ORGO | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-GORE | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-GOOR | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-GOGO | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-GOGR | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-GRRE | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-GROR | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-GRGO | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-GRGR | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-AQRE | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-AQOR | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-AQGO | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-AQGR | 20 (40 μL) | 200 μL |
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| UBA1-ELK3-20-AQAQ | 20 (40 μL) | 200 μL |
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ELK3 Gene Summary
This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Gene Name: ELK3, ETS Transcription Factor
Chromosome: CHR12: 96588206 -96661606
Locus: 12q23.1
UBA1 Gene Summary
The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]
Gene Name: Ubiquitin Like Modifier Activating Enzyme 1
Chromosome: CHRX: 47050198 -47074527
Locus: Xp11.3
Gene Diseases
The UBA1 ELK3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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