UBE2D1-MFSD11 Fusion FISH Probe
The UBE2D1-MFSD11 Fusion FISH Probe is used to confirm a fusion of the UBE2D1 and MFSD11 genes. The fusion of the UBE2D1 and MFSD11 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBE2D1-MFSD11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-RERE | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-REOR | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-REGO | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-REGR | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-REAQ | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-ORRE | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-OROR | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-ORGO | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-GORE | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-GOOR | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-GOGO | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-GOGR | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-GRRE | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-GROR | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-GRGO | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-GRGR | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-AQRE | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-AQOR | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-AQGO | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-AQGR | 20 (40 μL) | 200 μL |
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| UBE2D1-MFSD11-20-AQAQ | 20 (40 μL) | 200 μL |
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UBE2D1 Gene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Gene Name: Ubiquitin Conjugating Enzyme E2 D1
Chromosome: CHR10: 60094738 -60130513
Locus: 10q21.1
MFSD11 Gene Summary
The Major Facilitator Superfamily Domain Containing 11 (MFSD11) gene is located on chr17 :74732646-74775336 at 17q25.1-q25.2.
Gene Name: Major Facilitator Superfamily Domain Containing 11
Chromosome: CHR17: 74732646 -74775336
Locus: 17q25.1-q25.2
Gene Diseases
The UBE2D1 MFSD11 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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