UBE2G2-ABCG1 Fusion FISH Probe
The UBE2G2-ABCG1 Fusion FISH Probe is used to confirm a fusion of the UBE2G2 and ABCG1 genes. The fusion of the UBE2G2 and ABCG1 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBE2G2-ABCG1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-RERE | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-REOR | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-REGO | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-REGR | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-REAQ | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-ORRE | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-OROR | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-ORGO | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-GORE | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-GOOR | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-GOGO | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-GOGR | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-GRRE | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-GROR | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-GRGO | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-GRGR | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-AQRE | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-AQOR | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-AQGO | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-AQGR | 20 (40 μL) | 200 μL |
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| UBE2G2-ABCG1-20-AQAQ | 20 (40 μL) | 200 μL |
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UBE2G2 Gene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Gene Name: Ubiquitin Conjugating Enzyme E2 G2
Chromosome: CHR21: 46188494 -46221751
Locus: 21q22.3
ABCG1 Gene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily G Member 1
Chromosome: CHR21: 43619798 -43717354
Locus: 21q22.3
Gene Diseases
The UBE2G2 ABCG1 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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