UBE2J1-RRAGD Fusion FISH Probe
The UBE2J1-RRAGD Fusion FISH Probe is used to confirm a fusion of the UBE2J1 and RRAGD genes. The fusion of the UBE2J1 and RRAGD genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBE2J1-RRAGD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-RERE | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-REOR | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-REGO | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-REGR | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-REAQ | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-ORRE | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-OROR | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-ORGO | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-GORE | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-GOOR | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-GOGO | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-GOGR | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-GRRE | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-GROR | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-GRGO | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-GRGR | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-AQRE | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-AQOR | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-AQGO | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-AQGR | 20 (40 μL) | 200 μL |
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| UBE2J1-RRAGD-20-AQAQ | 20 (40 μL) | 200 μL |
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UBE2J1 Gene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system. [provided by RefSeq, Jul 2008]
Gene Name: Ubiquitin Conjugating Enzyme E2 J1
Chromosome: CHR6: 90036343 -90062619
Locus: 6q15
RRAGD Gene Summary
RRAGD is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.[supplied by OMIM, Apr 2004]
Gene Name: Ras Related GTP Binding D
Chromosome: CHR6: 90074334 -90121995
Locus: 6q15
Gene Diseases
The UBE2J1 RRAGD Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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