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UBE2O-RNF213 Fusion FISH Probe

The UBE2O-RNF213 Fusion FISH Probe is used to confirm a fusion of the UBE2O and RNF213 genes. The fusion of the UBE2O and RNF213 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
UBE2O-RNF213-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
UBE2O-RNF213-20-RERE 20 (40 μL) 200 μL
UBE2O-RNF213-20-REOR 20 (40 μL) 200 μL
UBE2O-RNF213-20-REGO 20 (40 μL) 200 μL
UBE2O-RNF213-20-REGR 20 (40 μL) 200 μL
UBE2O-RNF213-20-REAQ 20 (40 μL) 200 μL
UBE2O-RNF213-20-ORRE 20 (40 μL) 200 μL
UBE2O-RNF213-20-OROR 20 (40 μL) 200 μL
UBE2O-RNF213-20-ORGO 20 (40 μL) 200 μL
UBE2O-RNF213-20-ORAQ 20 (40 μL) 200 μL
UBE2O-RNF213-20-GORE 20 (40 μL) 200 μL
UBE2O-RNF213-20-GOOR 20 (40 μL) 200 μL
UBE2O-RNF213-20-GOGO 20 (40 μL) 200 μL
UBE2O-RNF213-20-GOGR 20 (40 μL) 200 μL
UBE2O-RNF213-20-GOAQ 20 (40 μL) 200 μL
UBE2O-RNF213-20-GRRE 20 (40 μL) 200 μL
UBE2O-RNF213-20-GROR 20 (40 μL) 200 μL
UBE2O-RNF213-20-GRGO 20 (40 μL) 200 μL
UBE2O-RNF213-20-GRGR 20 (40 μL) 200 μL
UBE2O-RNF213-20-GRAQ 20 (40 μL) 200 μL
UBE2O-RNF213-20-AQRE 20 (40 μL) 200 μL
UBE2O-RNF213-20-AQOR 20 (40 μL) 200 μL
UBE2O-RNF213-20-AQGO 20 (40 μL) 200 μL
UBE2O-RNF213-20-AQGR 20 (40 μL) 200 μL
UBE2O-RNF213-20-AQAQ 20 (40 μL) 200 μL

RNF213 Gene Summary

This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]

Gene Name: Ring Finger Protein 213

Chromosome: CHR17: 78234666 -78370086

Locus: 17q25.3

UBE2O Gene Summary

The Ubiquitin Conjugating Enzyme E2 O (UBE2O) gene is located on chr17 :74385612-74449288 at 17q25.1.

Gene Name: Ubiquitin Conjugating Enzyme E2 O

Chromosome: CHR17: 74385612 -74449288

Locus: 17q25.1

Gene Diseases

The UBE2O RNF213 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.