UBTF-FOXP1 Fusion FISH Probe
The UBTF-FOXP1 Fusion FISH Probe is used to confirm a fusion of the UBTF and FOXP1 genes. The fusion of the UBTF and FOXP1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBTF-FOXP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-RERE | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-REOR | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-REGO | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-REGR | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-REAQ | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-ORRE | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-OROR | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-ORGO | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-GORE | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-GOOR | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-GOGO | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-GOGR | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-GRRE | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-GROR | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-GRGO | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-GRGR | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-AQRE | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-AQOR | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-AQGO | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-AQGR | 20 (40 μL) | 200 μL |
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| UBTF-FOXP1-20-AQAQ | 20 (40 μL) | 200 μL |
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UBTF Gene Summary
This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011]
Gene Name: Upstream Binding Transcription Factor, RNA Polymerase I
Chromosome: CHR17: 42282400 -42298994
Locus: 17q21.31
FOXP1 Gene Summary
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Forkhead Box P1
Chromosome: CHR3: 71004735 -71633140
Locus: 3p13
Gene Diseases
The UBTF FOXP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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