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UGP2-PLEKHM3 Fusion FISH Probe

The UGP2-PLEKHM3 Fusion FISH Probe is used to confirm a fusion of the UGP2 and PLEKHM3 genes. The fusion of the UGP2 and PLEKHM3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
UGP2-PLEKHM3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-RERE 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-REOR 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-REGO 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-REGR 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-REAQ 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-ORRE 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-OROR 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-ORGO 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-ORAQ 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-GORE 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-GOOR 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-GOGO 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-GOGR 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-GOAQ 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-GRRE 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-GROR 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-GRGO 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-GRGR 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-GRAQ 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-AQRE 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-AQOR 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-AQGO 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-AQGR 20 (40 μL) 200 μL
UGP2-PLEKHM3-20-AQAQ 20 (40 μL) 200 μL

UGP2 Gene Summary

The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: UDP-glucose Pyrophosphorylase 2

Chromosome: CHR2: 64068097 -64118696

Locus: 2p15

PLEKHM3 Gene Summary

The Pleckstrin Homology Domain Containing M3 (PLEKHM3) gene is located on chr2 :208686011-208890284 at 2q33.3.

Gene Name: Pleckstrin Homology Domain Containing M3

Chromosome: CHR2: 208686011 -208890284

Locus: 2q33.3

Gene Diseases

The UGP2 PLEKHM3 Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.