VANGL2-PDE4DIP Fusion FISH Probe
The VANGL2-PDE4DIP Fusion FISH Probe is used to confirm a fusion of the VANGL2 and PDE4DIP genes. The fusion of the VANGL2 and PDE4DIP genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VANGL2-PDE4DIP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-RERE | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-REOR | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-REGO | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-REGR | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-REAQ | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-ORRE | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-OROR | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-ORGO | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-ORAQ | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-GORE | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-GOOR | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-GOGO | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-GOGR | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-GOAQ | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-GRRE | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-GROR | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-GRGO | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-GRGR | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-GRAQ | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-AQRE | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-AQOR | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-AQGO | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-AQGR | 20 (40 μL) | 200 μL |
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| VANGL2-PDE4DIP-20-AQAQ | 20 (40 μL) | 200 μL |
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PDE4DIP Gene Summary
The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
Gene Name: Phosphodiesterase 4D Interacting Protein
Chromosome: CHR1: 144851423 -145039992
Locus: 1q21.2
VANGL2 Gene Summary
The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate. [provided by RefSeq, Sep 2011]
Gene Name: VANGL Planar Cell Polarity Protein 2
Chromosome: CHR1: 160370363 -160398468
Locus: 1q23.2
Gene Diseases
The VANGL2 PDE4DIP Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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