VARS-HSPA1L Fusion FISH Probe
The VARS-HSPA1L Fusion FISH Probe is used to confirm a fusion of the VARS and HSPA1L genes. The fusion of the VARS and HSPA1L genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VARS-HSPA1L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-RERE | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-REOR | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-REGO | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-REGR | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-REAQ | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-ORRE | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-OROR | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-ORGO | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-ORAQ | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-GORE | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-GOOR | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-GOGO | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-GOGR | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-GOAQ | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-GRRE | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-GROR | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-GRGO | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-GRGR | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-GRAQ | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-AQRE | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-AQOR | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-AQGO | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-AQGR | 20 (40 μL) | 200 μL |
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| VARS-HSPA1L-20-AQAQ | 20 (40 μL) | 200 μL |
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HSPA1L Gene Summary
This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq, Jul 2008]
Gene Name: Heat Shock Protein Family A (Hsp70) Member 1 Like
Chromosome: CHR6_dbb_hap3: 3062982 -3068422
Locus: 6p21.33
VARS Gene Summary
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]
Gene Name: Valyl-tRNA Synthetase
Chromosome: CHR6_dbb_hap3: 3030878 -3049294
Locus: 6p21.33
Gene Diseases
The VARS HSPA1L Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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