VAV2-COL27A1 Fusion FISH Probe
The VAV2-COL27A1 Fusion FISH Probe is used to confirm a fusion of the VAV2 and COL27A1 genes. The fusion of the VAV2 and COL27A1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VAV2-COL27A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-RERE | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-REOR | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-REGO | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-REGR | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-REAQ | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-ORRE | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-OROR | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-ORGO | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-GORE | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-GOOR | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-GOGO | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-GOGR | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-GRRE | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-GROR | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-GRGO | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-GRGR | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-AQRE | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-AQOR | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-AQGO | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-AQGR | 20 (40 μL) | 200 μL |
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| VAV2-COL27A1-20-AQAQ | 20 (40 μL) | 200 μL |
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VAV2 Gene Summary
VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Gene Name: Vav Guanine Nucleotide Exchange Factor 2
Chromosome: CHR9: 136627015 -136857446
Locus: 9q34.2
COL27A1 Gene Summary
This gene encodes a member of the fibrillar collagen family, and plays a role during the calcification of cartilage and the transition of cartilage to bone. The encoded protein product is a preproprotein. It includes an N-terminal signal peptide, which is followed by an N-terminal propetide, mature peptide and a C-terminal propeptide. The N-terminal propeptide contains thrombospondin N-terminal-like and laminin G-like domains. The mature peptide is a major triple-helical region. The C-terminal propeptide, also known as COLFI domain, plays crucial roles in tissue growth and repair. Mutations in this gene cause Steel syndrome. Alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Sep 2014]
Gene Name: Collagen Type XXVII Alpha 1 Chain
Chromosome: CHR9: 116918230 -117072975
Locus: 9q32
Gene Diseases
The VAV2 COL27A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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