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VAV2-FNBP1 Fusion FISH Probe

The VAV2-FNBP1 Fusion FISH Probe is used to confirm a fusion of the VAV2 and FNBP1 genes. The fusion of the VAV2 and FNBP1 genes has been associated with Lymphoid Neoplasm Diffuse Large B-cell Lymphoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
VAV2-FNBP1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
VAV2-FNBP1-20-RERE 20 (40 μL) 200 μL
VAV2-FNBP1-20-REOR 20 (40 μL) 200 μL
VAV2-FNBP1-20-REGO 20 (40 μL) 200 μL
VAV2-FNBP1-20-REGR 20 (40 μL) 200 μL
VAV2-FNBP1-20-REAQ 20 (40 μL) 200 μL
VAV2-FNBP1-20-ORRE 20 (40 μL) 200 μL
VAV2-FNBP1-20-OROR 20 (40 μL) 200 μL
VAV2-FNBP1-20-ORGO 20 (40 μL) 200 μL
VAV2-FNBP1-20-ORAQ 20 (40 μL) 200 μL
VAV2-FNBP1-20-GORE 20 (40 μL) 200 μL
VAV2-FNBP1-20-GOOR 20 (40 μL) 200 μL
VAV2-FNBP1-20-GOGO 20 (40 μL) 200 μL
VAV2-FNBP1-20-GOGR 20 (40 μL) 200 μL
VAV2-FNBP1-20-GOAQ 20 (40 μL) 200 μL
VAV2-FNBP1-20-GRRE 20 (40 μL) 200 μL
VAV2-FNBP1-20-GROR 20 (40 μL) 200 μL
VAV2-FNBP1-20-GRGO 20 (40 μL) 200 μL
VAV2-FNBP1-20-GRGR 20 (40 μL) 200 μL
VAV2-FNBP1-20-GRAQ 20 (40 μL) 200 μL
VAV2-FNBP1-20-AQRE 20 (40 μL) 200 μL
VAV2-FNBP1-20-AQOR 20 (40 μL) 200 μL
VAV2-FNBP1-20-AQGO 20 (40 μL) 200 μL
VAV2-FNBP1-20-AQGR 20 (40 μL) 200 μL
VAV2-FNBP1-20-AQAQ 20 (40 μL) 200 μL

VAV2 Gene Summary

VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Gene Name: Vav Guanine Nucleotide Exchange Factor 2

Chromosome: CHR9: 136627015 -136857446

Locus: 9q34.2

FNBP1 Gene Summary

The protein encoded by this gene is a member of the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, a second coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not been demonstrated yet in human. [provided by RefSeq, Jul 2008]

Gene Name: Formin Binding Protein 1

Chromosome: CHR9: 132649465 -132805473

Locus: 9q34.11

Gene Diseases

The VAV2 FNBP1 Fusion has been associated with the following diseases:

Disease Name
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.