VIM-STAT6 Fusion FISH Probe
The VIM-STAT6 Fusion FISH Probe is used to confirm a fusion of the VIM and STAT6 genes. The fusion of the VIM and STAT6 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VIM-STAT6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-RERE | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-REOR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-REGO | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-REGR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-REAQ | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-ORRE | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-OROR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-ORGO | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-ORAQ | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GORE | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GOOR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GOGO | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GOGR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GOAQ | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GRRE | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GROR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GRGO | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GRGR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GRAQ | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-AQRE | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-AQOR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-AQGO | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-AQGR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-AQAQ | 20 (40 μL) | 200 μL |
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STAT6 Gene Summary
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Name: Signal Transducer And Activator Of Transcription 6
Chromosome: CHR12: 57489186 -57505196
Locus: 12q13.3
VIM Gene Summary
This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017]
Gene Name: Vimentin
Chromosome: CHR10: 17270257 -17279592
Locus: 10p13
Gene Diseases
The VIM STAT6 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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