VLDLR-SLC1A1 Fusion FISH Probe
The VLDLR-SLC1A1 Fusion FISH Probe is used to confirm a fusion of the VLDLR and SLC1A1 genes. The fusion of the VLDLR and SLC1A1 genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VLDLR-SLC1A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-RERE | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-REOR | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-REGO | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-REGR | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-REAQ | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-ORRE | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-OROR | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-ORGO | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-GORE | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-GOOR | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-GOGO | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-GOGR | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-GRRE | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-GROR | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-GRGO | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-GRGR | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-AQRE | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-AQOR | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-AQGO | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-AQGR | 20 (40 μL) | 200 μL |
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| VLDLR-SLC1A1-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC1A1 Gene Summary
This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. [provided by RefSeq, Mar 2010]
Gene Name: Solute Carrier Family 1 Member 1
Chromosome: CHR9: 4490426 -4587469
Locus: 9p24.2
VLDLR Gene Summary
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq, Aug 2009]
Gene Name: Very Low Density Lipoprotein Receptor
Chromosome: CHR9: 2621792 -2654485
Locus: 9p24.2
Gene Diseases
The VLDLR SLC1A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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