VPS13D-MFN2 Fusion FISH Probe
The VPS13D-MFN2 Fusion FISH Probe is used to confirm a fusion of the VPS13D and MFN2 genes. The fusion of the VPS13D and MFN2 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VPS13D-MFN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-RERE | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-REOR | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-REGO | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-REGR | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-REAQ | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-ORRE | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-OROR | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-ORGO | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-GORE | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-GOOR | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-GOGO | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-GOGR | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-GRRE | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-GROR | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-GRGO | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-GRGR | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-AQRE | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-AQOR | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-AQGO | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-AQGR | 20 (40 μL) | 200 μL |
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| VPS13D-MFN2-20-AQAQ | 20 (40 μL) | 200 μL |
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MFN2 Gene Summary
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Mitofusin 2
Chromosome: CHR1: 12040237 -12073572
Locus: 1p36.22
VPS13D Gene Summary
This gene encodes a protein belonging to the vacuolar-protein-sorting-13 gene family. In yeast, vacuolar-protein-sorting-13 proteins are involved in trafficking of membrane proteins between the trans-Golgi network and the prevacuolar compartment. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Vacuolar Protein Sorting 13 Homolog D
Chromosome: CHR1: 12290112 -12572098
Locus: 1p36.22-p36.21
Gene Diseases
The VPS13D MFN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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