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ZBTB20-PGD Fusion FISH Probe

The ZBTB20-PGD Fusion FISH Probe is used to confirm a fusion of the ZBTB20 and PGD genes. The fusion of the ZBTB20 and PGD genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ZBTB20-PGD-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ZBTB20-PGD-20-RERE 20 (40 μL) 200 μL
ZBTB20-PGD-20-REOR 20 (40 μL) 200 μL
ZBTB20-PGD-20-REGO 20 (40 μL) 200 μL
ZBTB20-PGD-20-REGR 20 (40 μL) 200 μL
ZBTB20-PGD-20-REAQ 20 (40 μL) 200 μL
ZBTB20-PGD-20-ORRE 20 (40 μL) 200 μL
ZBTB20-PGD-20-OROR 20 (40 μL) 200 μL
ZBTB20-PGD-20-ORGO 20 (40 μL) 200 μL
ZBTB20-PGD-20-ORAQ 20 (40 μL) 200 μL
ZBTB20-PGD-20-GORE 20 (40 μL) 200 μL
ZBTB20-PGD-20-GOOR 20 (40 μL) 200 μL
ZBTB20-PGD-20-GOGO 20 (40 μL) 200 μL
ZBTB20-PGD-20-GOGR 20 (40 μL) 200 μL
ZBTB20-PGD-20-GOAQ 20 (40 μL) 200 μL
ZBTB20-PGD-20-GRRE 20 (40 μL) 200 μL
ZBTB20-PGD-20-GROR 20 (40 μL) 200 μL
ZBTB20-PGD-20-GRGO 20 (40 μL) 200 μL
ZBTB20-PGD-20-GRGR 20 (40 μL) 200 μL
ZBTB20-PGD-20-GRAQ 20 (40 μL) 200 μL
ZBTB20-PGD-20-AQRE 20 (40 μL) 200 μL
ZBTB20-PGD-20-AQOR 20 (40 μL) 200 μL
ZBTB20-PGD-20-AQGO 20 (40 μL) 200 μL
ZBTB20-PGD-20-AQGR 20 (40 μL) 200 μL
ZBTB20-PGD-20-AQAQ 20 (40 μL) 200 μL

PGD Gene Summary

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]

Gene Name: Phosphogluconate Dehydrogenase

Chromosome: CHR1: 10459084 -10480201

Locus: 1p36.22

ZBTB20 Gene Summary

This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]

Gene Name: Zinc Finger And BTB Domain Containing 20

Chromosome: CHR3: 114056946 -114866127

Locus: 3q13.31

Gene Diseases

The ZBTB20 PGD Fusion has been associated with the following diseases:

Disease Name
Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.