ZDBF2-PSMD1 Fusion FISH Probe
The ZDBF2-PSMD1 Fusion FISH Probe is used to confirm a fusion of the ZDBF2 and PSMD1 genes. The fusion of the ZDBF2 and PSMD1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ZDBF2-PSMD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ZDBF2-PSMD1-20-AQAQ | 20 (40 μL) | 200 μL |
|
PSMD1 Gene Summary
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2010]
Gene Name: Proteasome 26S Subunit, Non-ATPase 1
Chromosome: CHR2: 231921577 -232037540
Locus: 2q37.1
ZDBF2 Gene Summary
This gene encodes a protein containing DBF4-type zinc finger domains. This gene is imprinted and paternally expressed in lymphocytes but is more stochastically expressed in the placenta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Gene Name: Zinc Finger DBF-type Containing 2
Chromosome: CHR2: 207139522 -207179148
Locus: 2q33.3
Gene Diseases
The ZDBF2 PSMD1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|