ZMYND11-CDH18 Fusion FISH Probe
The ZMYND11-CDH18 Fusion FISH Probe is used to confirm a fusion of the ZMYND11 and CDH18 genes. The fusion of the ZMYND11 and CDH18 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZMYND11-CDH18-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-RERE | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-REOR | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-REGO | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-REGR | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-REAQ | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-ORRE | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-OROR | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-ORGO | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-GORE | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-GOOR | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-GOGO | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-GOGR | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-GRRE | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-GROR | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-GRGO | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-GRGR | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-AQRE | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-AQOR | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-AQGO | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-AQGR | 20 (40 μL) | 200 μL |
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| ZMYND11-CDH18-20-AQAQ | 20 (40 μL) | 200 μL |
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CDH18 Gene Summary
This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
Gene Name: Cadherin 18
Chromosome: CHR5: 19473154 -19988353
Locus: 5p14.3
ZMYND11 Gene Summary
The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Zinc Finger MYND-type Containing 11
Chromosome: CHR10: 180404 -300577
Locus: 10p15.3
Gene Diseases
The ZMYND11 CDH18 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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