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ZNF146-PGPEP1 Fusion FISH Probe

The ZNF146-PGPEP1 Fusion FISH Probe is used to confirm a fusion of the ZNF146 and PGPEP1 genes. The fusion of the ZNF146 and PGPEP1 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ZNF146-PGPEP1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-RERE 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-REOR 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-REGO 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-REGR 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-REAQ 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-ORRE 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-OROR 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-ORGO 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-ORAQ 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-GORE 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-GOOR 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-GOGO 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-GOGR 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-GOAQ 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-GRRE 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-GROR 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-GRGO 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-GRGR 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-GRAQ 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-AQRE 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-AQOR 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-AQGO 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-AQGR 20 (40 μL) 200 μL
ZNF146-PGPEP1-20-AQAQ 20 (40 μL) 200 μL

ZNF146 Gene Summary

The Zinc Finger Protein 146 (ZNF146) gene is located on chr19 :36705503-36729675 at 19q13.12.

Gene Name: Zinc Finger Protein 146

Chromosome: CHR19: 36705503 -36729675

Locus: 19q13.12

PGPEP1 Gene Summary

The gene encodes a cysteine protease and member of the peptidase C15 family of proteins. The encoded protein cleaves amino terminal pyroglutamate residues from protein substrates including thyrotropin-releasing hormone and other neuropeptides. Expression of this gene may be downregulated in colorectal cancer, while activity of the encoded protein may be negatively correlated with cancer progression in colorectal cancer patients. Activity of the encoded protease may also be altered in other disease states including in liver cirrhosis, which is associated with reduced protease activity, and in necrozoospermia, which is associated with elevated protease activity. [provided by RefSeq, Jul 2016]

Gene Name: Pyroglutamyl-peptidase I

Chromosome: CHR19: 18451407 -18480763

Locus: 19p13.11

Gene Diseases

The ZNF146 PGPEP1 Fusion has been associated with the following diseases:

Disease Name
Uterine Corpus Endometrial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.