ZNF175-CYP27B1 Fusion FISH Probe
The ZNF175-CYP27B1 Fusion FISH Probe is used to confirm a fusion of the ZNF175 and CYP27B1 genes. The fusion of the ZNF175 and CYP27B1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF175-CYP27B1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF175-CYP27B1-20-AQAQ | 20 (40 μL) | 200 μL |
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CYP27B1 Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I. [provided by RefSeq, Jul 2008]
Gene Name: Cytochrome P450 Family 27 Subfamily B Member 1
Chromosome: CHR12: 58156116 -58160976
Locus: 12q14.1
ZNF175 Gene Summary
The Zinc Finger Protein 175 (ZNF175) gene is located on chr19 :52074530-52092991 at 19q13.41.
Gene Name: Zinc Finger Protein 175
Chromosome: CHR19: 52074530 -52092991
Locus: 19q13.41
Gene Diseases
The ZNF175 CYP27B1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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