ZNF184-CD2AP Fusion FISH Probe
The ZNF184-CD2AP Fusion FISH Probe is used to confirm a fusion of the ZNF184 and CD2AP genes. The fusion of the ZNF184 and CD2AP genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF184-CD2AP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF184-CD2AP-20-AQAQ | 20 (40 μL) | 200 μL |
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ZNF184 Gene Summary
The protein encoded by this gene is predicted to be a Kruppel C2H2-type zinc-finger protein family member. Sequence analysis predicts that the protein contains two Kruppel associated box (KRAB) boxes in the N-terminus and highly conserved zinc finger motifs at the C-terminus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016]
Gene Name: Zinc Finger Protein 184
Chromosome: CHR6: 27418520 -27440897
Locus: 6p22.1
CD2AP Gene Summary
This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq, Jul 2008]
Gene Name: CD2 Associated Protein
Chromosome: CHR6: 47445524 -47594996
Locus: 6p12.3
Gene Diseases
The ZNF184 CD2AP Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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