ZNF229-ERCC1 Fusion FISH Probe
The ZNF229-ERCC1 Fusion FISH Probe is used to confirm a fusion of the ZNF229 and ERCC1 genes. The fusion of the ZNF229 and ERCC1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ZNF229-ERCC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ZNF229-ERCC1-20-AQAQ | 20 (40 μL) | 200 μL |
|
ERCC1 Gene Summary
The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq, Oct 2009]
Gene Name: ERCC Excision Repair 1, Endonuclease Non-catalytic Subunit
Chromosome: CHR19: 45910590 -45927177
Locus: 19q13.32
ZNF229 Gene Summary
The Zinc Finger Protein 229 (ZNF229) gene is located on chr19 :44930425-44952665 at 19q13.31.
Gene Name: Zinc Finger Protein 229
Chromosome: CHR19: 44930425 -44952665
Locus: 19q13.31
Gene Diseases
The ZNF229 ERCC1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|