ZNF251-CHMP4C Fusion FISH Probe
The ZNF251-CHMP4C Fusion FISH Probe is used to confirm a fusion of the ZNF251 and CHMP4C genes. The fusion of the ZNF251 and CHMP4C genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF251-CHMP4C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF251-CHMP4C-20-AQAQ | 20 (40 μL) | 200 μL |
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ZNF251 Gene Summary
The Zinc Finger Protein 251 (ZNF251) gene is located on chr8 :145946293-145980970 at 8q24.3.
Gene Name: Zinc Finger Protein 251
Chromosome: CHR8: 145946293 -145980970
Locus: 8q24.3
CHMP4C Gene Summary
CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]
Gene Name: Charged Multivesicular Body Protein 4C
Chromosome: CHR8: 82644687 -82671748
Locus: 8q21.13
Gene Diseases
The ZNF251 CHMP4C Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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