ZNF274-CACNA2D4 Fusion FISH Probe
The ZNF274-CACNA2D4 Fusion FISH Probe is used to confirm a fusion of the ZNF274 and CACNA2D4 genes. The fusion of the ZNF274 and CACNA2D4 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF274-CACNA2D4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF274-CACNA2D4-20-AQAQ | 20 (40 μL) | 200 μL |
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ZNF274 Gene Summary
This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals. [provided by RefSeq, Jul 2008]
Gene Name: Zinc Finger Protein 274
Chromosome: CHR19: 58694395 -58724927
Locus: 19q13.43
CACNA2D4 Gene Summary
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Gene Name: Calcium Voltage-gated Channel Auxiliary Subunit Alpha2delta 4
Chromosome: CHR12: 1901122 -2027870
Locus: 12p13.33
Gene Diseases
The ZNF274 CACNA2D4 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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