ZNF546-HNRNPD Fusion FISH Probe
The ZNF546-HNRNPD Fusion FISH Probe is used to confirm a fusion of the ZNF546 and HNRNPD genes. The fusion of the ZNF546 and HNRNPD genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF546-HNRNPD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF546-HNRNPD-20-AQAQ | 20 (40 μL) | 200 μL |
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HNRNPD Gene Summary
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]
Gene Name: Heterogeneous Nuclear Ribonucleoprotein D
Chromosome: CHR4: 83274466 -83295149
Locus: 4q21.22
ZNF546 Gene Summary
The Zinc Finger Protein 546 (ZNF546) gene is located on chr19 :40502942-40523514 at 19q13.2.
Gene Name: Zinc Finger Protein 546
Chromosome: CHR19: 40502942 -40523514
Locus: 19q13.2
Gene Diseases
The ZNF546 HNRNPD Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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