ZNF587-AURKC Fusion FISH Probe
The ZNF587-AURKC Fusion FISH Probe is used to confirm a fusion of the ZNF587 and AURKC genes. The fusion of the ZNF587 and AURKC genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF587-AURKC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF587-AURKC-20-AQAQ | 20 (40 μL) | 200 μL |
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AURKC Gene Summary
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Name: Aurora Kinase C
Chromosome: CHR19: 57742376 -57746916
Locus: 19q13.43
ZNF587 Gene Summary
The Zinc Finger Protein 587 (ZNF587) gene is located on chr19 :58361180-58376491 at 19q13.43.
Gene Name: Zinc Finger Protein 587
Chromosome: CHR19: 58361180 -58376491
Locus: 19q13.43
Gene Diseases
The ZNF587 AURKC Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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