ZNF638-EXOC6B Fusion FISH Probe
The ZNF638-EXOC6B Fusion FISH Probe is used to confirm a fusion of the ZNF638 and EXOC6B genes. The fusion of the ZNF638 and EXOC6B genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF638-EXOC6B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF638-EXOC6B-20-AQAQ | 20 (40 μL) | 200 μL |
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EXOC6B Gene Summary
This gene encodes a protein which is a part of the evolutionarily conserved exocyst, a multimeric protein complex necessary for exocytosis, which in turn, is crucial for cell growth, polarity and migration. Disruption of this gene may be associated with phenotypes exhibiting multiple symptoms including intellectual disability and developmental delay (DD). [provided by RefSeq, Jun 2016]
Gene Name: Exocyst Complex Component 6B
Chromosome: CHR2: 72406443 -73053177
Locus: 2p13.2
ZNF638 Gene Summary
The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: MH1, MH2 (repeated three times) and MH3. It is associated with packaging, transferring, or processing transcripts. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Zinc Finger Protein 638
Chromosome: CHR2: 71558888 -71662189
Locus: 2p13.3-p13.2
Gene Diseases
The ZNF638 EXOC6B Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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