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ZNF653-PDE4A Fusion FISH Probe

The ZNF653-PDE4A Fusion FISH Probe is used to confirm a fusion of the ZNF653 and PDE4A genes. The fusion of the ZNF653 and PDE4A genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ZNF653-PDE4A-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ZNF653-PDE4A-20-RERE 20 (40 μL) 200 μL
ZNF653-PDE4A-20-REOR 20 (40 μL) 200 μL
ZNF653-PDE4A-20-REGO 20 (40 μL) 200 μL
ZNF653-PDE4A-20-REGR 20 (40 μL) 200 μL
ZNF653-PDE4A-20-REAQ 20 (40 μL) 200 μL
ZNF653-PDE4A-20-ORRE 20 (40 μL) 200 μL
ZNF653-PDE4A-20-OROR 20 (40 μL) 200 μL
ZNF653-PDE4A-20-ORGO 20 (40 μL) 200 μL
ZNF653-PDE4A-20-ORAQ 20 (40 μL) 200 μL
ZNF653-PDE4A-20-GORE 20 (40 μL) 200 μL
ZNF653-PDE4A-20-GOOR 20 (40 μL) 200 μL
ZNF653-PDE4A-20-GOGO 20 (40 μL) 200 μL
ZNF653-PDE4A-20-GOGR 20 (40 μL) 200 μL
ZNF653-PDE4A-20-GOAQ 20 (40 μL) 200 μL
ZNF653-PDE4A-20-GRRE 20 (40 μL) 200 μL
ZNF653-PDE4A-20-GROR 20 (40 μL) 200 μL
ZNF653-PDE4A-20-GRGO 20 (40 μL) 200 μL
ZNF653-PDE4A-20-GRGR 20 (40 μL) 200 μL
ZNF653-PDE4A-20-GRAQ 20 (40 μL) 200 μL
ZNF653-PDE4A-20-AQRE 20 (40 μL) 200 μL
ZNF653-PDE4A-20-AQOR 20 (40 μL) 200 μL
ZNF653-PDE4A-20-AQGO 20 (40 μL) 200 μL
ZNF653-PDE4A-20-AQGR 20 (40 μL) 200 μL
ZNF653-PDE4A-20-AQAQ 20 (40 μL) 200 μL

PDE4A Gene Summary

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Gene Name: Phosphodiesterase 4A

Chromosome: CHR19: 10527448 -10580307

Locus: 19p13.2

ZNF653 Gene Summary

The Zinc Finger Protein 653 (ZNF653) gene is located on chr19 :11594241-11616738 at 19p13.2.

Gene Name: Zinc Finger Protein 653

Chromosome: CHR19: 11594241 -11616738

Locus: 19p13.2

Gene Diseases

The ZNF653 PDE4A Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.