ZNF684-EIF2B3 Fusion FISH Probe
The ZNF684-EIF2B3 Fusion FISH Probe is used to confirm a fusion of the ZNF684 and EIF2B3 genes. The fusion of the ZNF684 and EIF2B3 genes has been associated with Testicular Germ Cell Tumors. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF684-EIF2B3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF684-EIF2B3-20-AQAQ | 20 (40 μL) | 200 μL |
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EIF2B3 Gene Summary
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Name: Eukaryotic Translation Initiation Factor 2B Subunit Gamma
Chromosome: CHR1: 45316193 -45452361
Locus: 1p34.1
ZNF684 Gene Summary
The Zinc Finger Protein 684 (ZNF684) gene is located on chr1 :40997232-41013841 at 1p34.2.
Gene Name: Zinc Finger Protein 684
Chromosome: CHR1: 40997232 -41013841
Locus: 1p34.2
Gene Diseases
The ZNF684 EIF2B3 Fusion has been associated with the following diseases:
| Disease Name |
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| Testicular Germ Cell Tumors |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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