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61B3-R FISH Probe

The 61B3-R FISH probe is designed to hybridize to the 61B3-R gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MID1-20-OR  (Standard Design) 20 (40 μL) 200 μL
MID1-20-RE 20 (40 μL) 200 μL
MID1-20-GO 20 (40 μL) 200 μL
MID1-20-GR 20 (40 μL) 200 μL
MID1-20-AQ 20 (40 μL) 200 μL
MID1-20-DIG 20 (40 μL) 200 μL
MID1-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]

Gene Details

Gene Symbol: MID1

Gene Name: Midline 1

Chromosome: CHRX: 10413349-10851809

Locus: Xp22.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: 61B3-R FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: MID1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping