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ABC35 FISH Probe

The ABC35 FISH probe is designed to hybridize to the ABC35 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CFTR-20-OR  (Standard Design) 20 (40 μL) 200 μL
CFTR-20-RE 20 (40 μL) 200 μL
CFTR-20-GO 20 (40 μL) 200 μL
CFTR-20-GR 20 (40 μL) 200 μL
CFTR-20-AQ 20 (40 μL) 200 μL
CFTR-20-DIG 20 (40 μL) 200 μL
CFTR-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. Channel activation is mediated by cycles of regulatory domain phosphorylation, ATP-binding by the nucleotide-binding domains, and ATP hydrolysis. Mutations in this gene cause cystic fibrosis, the most common lethal genetic disorder in populations of Northern European descent. The most frequently occurring mutation in cystic fibrosis, DeltaF508, results in impaired folding and trafficking of the encoded protein. Multiple pseudogenes have been identified in the human genome. [provided by RefSeq, Aug 2017]

Gene Details

Gene Symbol: CFTR

Gene Name: Cystic Fibrosis Transmembrane Conductance Regulator

Chromosome: CHR7: 117120016-117308718

Locus: 7q31.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ABC35 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: CFTR-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping