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ABCB1LB FISH Probe

The ABCB1LB FISH probe is designed to hybridize to the ABCB1LB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ABCB1-20-OR  (Standard Design) 20 (40 μL) 200 μL
ABCB1-20-RE 20 (40 μL) 200 μL
ABCB1-20-GO 20 (40 μL) 200 μL
ABCB1-20-GR 20 (40 μL) 200 μL
ABCB1-20-AQ 20 (40 μL) 200 μL
ABCB1-20-DIG 20 (40 μL) 200 μL
ABCB1-20-BIO 20 (40 μL) 200 μL

Gene Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. Mutations in this gene are associated with colchicine resistance and Inflammatory bowel disease 13. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Feb 2017]

Gene Details

Gene Symbol: ABCB1

Gene Name: ATP Binding Cassette Subfamily B Member 1

Chromosome: CHR7: 87133178-87342639

Locus: 7q21.12

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ABCB1LB FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ABCB1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping