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AML1T1 FISH Probe

The AML1T1 FISH probe is designed to hybridize to the AML1T1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RUNX1T1-20-OR  (Standard Design) 20 (40 μL) 200 μL
RUNX1T1-20-RE 20 (40 μL) 200 μL
RUNX1T1-20-GO 20 (40 μL) 200 μL
RUNX1T1-20-GR 20 (40 μL) 200 μL
RUNX1T1-20-AQ 20 (40 μL) 200 μL
RUNX1T1-20-DIG 20 (40 μL) 200 μL
RUNX1T1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]

Gene Details

Gene Symbol: RUNX1T1

Gene Name: RUNX1 Translocation Partner 1

Chromosome: CHR8: 92967194-93115454

Locus: 8q21.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: AML1T1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: RUNX1T1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping