AML3 FISH Probe
The AML3 FISH probe is designed to hybridize to the AML3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RUNX2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RUNX2-20-RE | 20 (40 μL) | 200 μL |  |
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| RUNX2-20-GO | 20 (40 μL) | 200 μL |  |
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| RUNX2-20-GR | 20 (40 μL) | 200 μL |  |
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| RUNX2-20-AQ | 20 (40 μL) | 200 μL |  |
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| RUNX2-20-DIG | 20 (40 μL) | 200 μL |  |
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| RUNX2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016]
Gene Details
Gene Symbol: RUNX2
Gene Name: Runt Related Transcription Factor 2
Chromosome: CHR6: 45296053-45518819
Locus: 6p21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AML3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RUNX2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping